Ligand Efficiency Indices for Drug Discovery

  • Author : Celerino Abad-Zapatero
  • Publsiher : Academic Press
  • Release : 22 January 2013
  • ISBN : 9780124046825
  • Page : 178 pages
  • Rating : 4/5 from 21 voters

Download or read online book entitled Ligand Efficiency Indices for Drug Discovery written by Celerino Abad-Zapatero and published by Academic Press. This book was released on 22 January 2013 with total page 178 pages. Available in PDF, EPUB and Kindle. Get best books that you want by click Get Book Button and Read as many books as you like. Book Excerpt : The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery Emphasizes the use of ‘new variables’ and more objective numerical methods to drive quicker and more effective drug discovery Presents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework

Ligand Efficiency Indices for Drug Discovery

Ligand Efficiency Indices for Drug Discovery
Author: Celerino Abad-Zapatero
Publisher: Academic Press
Relase: 2013-01-22
ISBN: 9780124046825
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