Long Non Coding RNA the Dark Side of the Genome

  • Author : Antonin Morillon
  • Publsiher : Iste Press - Elsevier
  • Release : 17 January 2018
  • ISBN : 1785482653
  • Page : 190 pages
  • Rating : 4/5 from 21 voters

Download or read online book entitled Long Non Coding RNA the Dark Side of the Genome written by Antonin Morillon and published by Iste Press - Elsevier. This book was released on 17 January 2018 with total page 190 pages. Available in PDF, EPUB and Kindle. Get best books that you want by click Get Book Button and Read as many books as you like. Book Excerpt : The dark side of the genome represents vast domains of the genome that are not encoding for proteins - the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms. This book offers a large review about the long non-coding RNA It presents the broad functional diversities of those molecules It presents pioneer works from the field Provides a comprehensive review of the field Presents fundamental and therapeutic interests

Long Non Coding RNA the Dark Side of the Genome

Long Non Coding RNA   the Dark Side of the Genome
Author: Antonin Morillon
Publisher: Iste Press - Elsevier
Relase: 2018-01-17
ISBN: 1785482653
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